Environmental or self-antigens and homotypic interactions induce BCR and Toll-like receptor (TLR) signaling, amplifying the reaction of CLL cells to other indicators from the microenvironment and rising the activation of anti-apoptotic and proliferation pathways.31,32 Genomic studies have determined recurrent mutations in genes regulating tumor mobile-microenvironment interactions, th... https://jonahr505ymc7.snack-blog.com/profile