Finally, clonidine improves neuraxial opioids and, together with fentanyl, interacts within an additive manner, which might reduce the dose of each part by 60% for postoperative analgesia. Clonidine treats superior blood pressure level by stimulating αtwo receptors while in the brainstem, which decreases peripheral vascular resistance, lowering blood pressure. https://socialmediatotal.com/story4827124/onolidine-fundamentals-explained