Slippery elm can help soothe the intestine, which may be beneficial if Lyme and kidney challenges are upsetting digestion . Milk thistle + SAM-e are great for liver/kidney support if organs are stressed. Also, probiotics might help cut down inflammation and support immune response L-theanine and melatonin may be used https://bestdogfleatreatment201382592.shotblogs.com/canine-arthritis-treatment-an-overview-52957277